With aging, people can often experience a decline in cognitive functioning, with memory and attention being the most commonly affected areas. This can impact your daily experience and lead to a decreased mental sharpness, forgetfulness and an overall lower quality of life.

So, what can be done to prevent, slow down or even reverse age-related cognitive decline?

Promising avenues of research show the use of some IV and peptide treatments, along with certain, high-quality supplements, and lifestyle changes have a measurable effect. The food you consume as well as the amounts of macronutrients and targeted micronutrients has an enormous impact on your experience of functionality and how you age in general. 

We believe that every body is unique, and based on advanced diagnostic testing, inquiry and observation, it's possible to find a diet and supplementation regimen that is personally tailored for optimal functioning. Despite that, there are some things that can benefit (almost) anyone in terms of food - like fresh, wild caught salmon with all of it's healthy fats and nutrients! This is in line with our general suggestion to try a Paleo-Meditteranean Lifestyle and Diet for overall optimal wellness.

Here’s a favorite, quick easy meal we have at home that supports brain health. Stay tuned after the recipe for more tips from integrative regenerative and cellular medicine to support your cognitive performance!  

Brain Food - Salmon & Salad Paleo-Mediterranean Recipe

Brain Food Salmon & Salad Ingredients

Brain Food Salmon Ingredients

• 2 lb Salmon Filet, skin on

• Olive oil for brushing

• Garlic Powder

• Salt and pepper

Brain Food Salad Ingredients

• Dark, leafy green mix

• Cole slaw or broccoli slaw mix

• Toasted walnuts

• Blueberries

• Fig Balsamic Vinegar

• Olive oil

• Salt and Pepper to Taste

Instructions

Brain Food Salmon Instructions

1. Preheat oven to 415

2. Place salmon filet on parchment covered cooking sheet

3. Brush with olive oil, sprinkle with garlic, salt and pepper

4. Bake for 15-20 minutes, until surface of salmon has white bubbles of fat on surface

Brain Food Salad Instructions

1. Toss veggies, nuts and berries in a large salad bowl.

2. Drizzle with vinegar and oil.

3. Sprinkle with salt and pepper.

Putting Together Your Brain Food Salmon & Salad

1. Serve the salmon over top of your salad mix.\

2. Enjoy!

Other Ways to Support Brain Health

Peptides Therapies

Several peptide therapies can help reduce inflammation, improve functioning of various pathways and support or reverse the effects of other conditions associated with age-related cognitive decline. 

Some peptides have been shown to have neuroprotective effects, which can help shield the brain from damage and promote healthy brain function. Peptide treatments that increase BDNF (brain-derived neurotrophic factor) levels, for instance, have shown promise in improving cognitive function in older adults as well as the ability to support the growth and maintenance of neurons, thereby improving memory and cognitive function in animal studies. In humans, BDNF levels have been found to decline with age, which may contribute to age-related cognitive decline.  

DIHEXA

DIHEXA is a synthetic peptide which functions by increasing the levels of brain-derived neurotrophic factor. It was created to significantly bolster cognitive functioning available in capsule form. This formula has been specifically formulated to cross the blood-brain barrier and promote the growth of new neurons and synapses - crucial components for cognitive enhancement.

Here are some additional amazing benefits of DIHEXA:

• Enhanced Focus and Cognitive Clarity: Since BDNF is essential for supporting the survival and growth of neurons, and for facilitating synaptic plasticity, DIHEXA can boost the brain's ability to adapt to new information. 
• Memory Improvement: Potential memory enhancement through DIHEXA is linked to its potent neurogenic effects. By binding to and activating HGF, this supplement can promote the formation of dendritic spines, which are crucial for memory storage and retrieval. This action cannot only help in forming new memory pathways but also can strengthen existing ones, thereby improving both short-term and long-term memory capabilities.
• Reduction of Brain Fog: DIHEXA's overall enhancement of synaptic connectivity and neuroplasticity improves synaptic efficiency and leads to clearer cognitive processing, allowing for quicker thinking and problem-solving, which directly combats the symptoms of brain fog. Additionally, the up-regulation of BDNF and HGF can contribute to a healthier neuronal environment, further clearing cognitive obscurities.
• Recovery Aid for Neurological Health: This supplement can play a part in the treatment protocol used in recovery from neurological injuries such as strokes, possibly helping to restore function afterward. It can accelerate the process of neurogenesis and angiogenesis, which are critical for repairing brain damage.
• Neuroinflammation Reduction: As mentioned, neuroinflammation is a common underlying factor in many neurodegenerative diseases and cognitive disorders. DIHEXA's modulation of HGF and BDNF not only supports neural growth and repair but also provides neuroprotective effects that can reduce inflammation and the associated neurotoxicity.

Despite all these powerful possibilities, it's important to consult with your healthcare partner before incorporating DIHEXA into your supplementation and peptide regimen.

High-Caliber, Targeted Supplementation

Supplements can help maximize brain function and provide beneficial nutrients that can assist in cognitive function. That said - we do not recommend indiscriminate supplement intake. It's important to work with an experienced specialist who can guide you in selecting supplements that are right for your need and goals.

Some supplements that we may offer at Medical Transformation Center to patients looking to support their cognitive functioning include:

RegenaBrainHealth

RegenaBrainHealth's formula is designed to maximize brain function by fostering healthy cognition, mood, and memory. It is designed to facilitate multiple facets of brain health, such as cellular energy production, mitochondrial functioning, and antioxidant protection. This supplement has an expertly curated blend of key ingredients designed to work synergistically to support cognition. Star ingredients in this blend are:

• Acetyl-L-Carnitine HCL (ALC), which aids in mitochondrial functioning and modulates inflammatory response. 
• Citicoline, bolstering your body's natural capacity to repair and regenerate neuronal cell membranes.
• Coffee Fruit Concentrate from whole fruit Coffea arabica to harness polyphenols and other nutrient-rich properties of the cherry, helping with memory and neuron health.
• L-alpha-Glycerylphosphorylcholine, from extremely refined soy lecithin and Phosphatidylserine, from sunflower lecithin - Both have been shown to possess neuroprotective effects as well as foster cognition.
• Ginkgo, from Ginkgo biloba leaf controlled to contain 24% ginkgo flavonglycosides and 6% terpene lactones. This boosts overall brain wellness, memory and concentration.

RegenaBrainHealth supplies the building blocks for brain phospholipids, which are the key structural components of neuron synapses. It is designed to facilitate multiple facets of brain health, such as cellular energy production, mitochondrial functioning, and antioxidant protection.  

RegenaOmegaPlus

RegenaOmegaPlus features an enhanced omega-3 fatty acid blend expertly-crafted to support cardiovascular, joint, hair, skin, cognitive, mental, bone and immune health. Formulated to promote peak absorption, this supplement has a high concentration of key ingredients plus synergistic pairings to encourage digestion and absorption. Key components are:

• Eicosapentaenoic acid (EPA), or purified omega-3 fatty acid in triglyceride form. This is sourced from high-quality, cold water fish (salmon, sardines and/or mackerel) and fosters brain health, emotional stability, skin health, healthy cholesterol levels, modulated immune system.
• Docosahexaenoic acid (DHA), or purified omega-3 fatty acid in triglyceride form, sourced from high-quality cold water fish (salmon, sardines and/or mackerel)
• Vitamin D3, Vitamin K1 and  Vitamin K2 enhance the effects of omega-3 fatty acids.

Our formula contains the highest-quality fish oils from fresh cold water fish that has been purified to filter out toxins and is presented in triglyceride form, which is the most potent and bioavailable form, with the addition of tocopherols to preserve their potency and fight against spoilage.  product supports your health in a variety of ways. RegenaOmegaPlus is particularly useful for brain and joint health, as well as cardiovascular health and general optimal aging. 

RegenaHeart&BrainHealth

RegenaHeart&BrainHealth's nutrients work in tandem to support a healthy homocysteine pathway, and integral part of your body's methylation process (integral to overall functioning). The lineup in this powerful blend is as follows:

• Riboflavin (as Riboflavin-5-Phosphate), which is essential for healthy homocysteine pathway function.
• Vitamin B6 (as Pyridoxal-5-Phosphate) also supports healthy homocysteine pathway function.
• Folate (as [6S]-5-methyltetrahydrofolate, glucosamine salt), in the bioavailable form essential for healthy homocysteine pathway function.
• Vitamin B12 (as Methylcobalamin), in the bioavailable form essential for healthy homocysteine pathway function.
• Trimethylglycine (TMG), to support healthy methylation.
• L-serine, which is an amino acid source of one-carbon units used in methylation reactions.

A balanced and efficient homocysteine pathway supplies the methyl and sulfur groups needed for biochemical processes like detoxification, proper immune function, optimal joint and cartilage structuring and brain and cardiovascular health. RegenaHeart&BrainHealth can be an excellent supplement for those with MTHFR gene mutations as well as anyone who needs cardiovascular support, has other methylation issues, or wants to support cognitive function.

Ketone Esters

Ketone Esters are great to help with energy, concentration levels, and carb cravings. At Regenavita, we offer KetoneAid KE4 Pro which provides a super-concentrated cherry-flavored formula featuring 50% Ketone Ester in 3, 60ml-format bottles. Please note that this is not intended for weight loss, but can be a part of your weight loss, energy or cognitive performance journey.

As with any supplement, it's essential to consult with a healthcare partner or specialist to get personalized details on the correct dosage for your body and goals. Some like to take KetoneAid KE4 Pro almost as a shot, others will dilute it in some cold water. Some use between 5-10ml of KE4 a day. We find that 1-2 tsp is a sweet spot for most. While certain athletes may use 1 bottle (30g of Ketone Ester, 60ml of Ke4), this could be too much, so, again, please consult with your health partner to determine dosage for your body.

RegenaDUltra

RegenaDUltra furnishes your body with an ultra-concentrated 10,000 IU (250 mcg) dose of vitamin D. Our blend supports the absorption of the most bioavailable form of vitamin D with the additions of other nutrients:

• Vitamin D3 (as Cholecalciferol), which is a fat-soluble vitamin shown to foster bone, cardiovascular and immune health. We have selected the form that has been shown most effective in supporting healthy human levels of the vitamin.
• Vitamins K, with K1 (as Phytonadione) and K2 (as MK-4) are fat-soluble vitamins that boost bone health. They are especially beneficial for cardiovascular health when combined with Vitamin D. 2000 mcg.
• Trans-Geranylgeraniol (GG), which supports healthy cellular function and the production of Vitamin K2.

RegenaDUltra creates a powerhouse for your bone, immune, and cardiovascular health. We've also added quillaja extract and medium chain triglycerides (MCTs) in a combination that boosts bioavailability – so you receive the maximum benefit possible.

As always, with any supplement, consult with your health parter or team before beginning anything new. This ensures that it is safe and beneficial for YOUR unique body and situation. Personalized medicine is a key tenet of the MTC Approach, which our products have been based on and inspired after decades of experience! Read Our Origins Story Here.

IV Nutrition Therapy

IVs aren’t just for hospitals anymore! This is a type of treatment that provides your body with specific nutrients, like vitamins and minerals. It can be used to replenish if your body is generally low in any nutrients, or for people with certain acute or chronic conditions.

Though eating nutritiously is always an important part of any health transformation plan, sometimes bodies need specific nutrients in amounts that they aren't able to obtain from food alone. Also, if you have any gut absorption issues, you're able to benefit from having nutrients delivered straight to their bloodstream via an IV. We've seen firsthand through our patients that a lot of people have gut permeability and absorption issues at the root of some of their cognitive symptoms.  

Because of this almost instant deliverability, IV therapy is one of the fastest ways to get important nutrients in your body. It is especially powerful when done in a sequence of 3-4 IVs at regular intervals. There are blends curated specifically for cognitive support. However, it's important to go to an IV specialist who has medical experience and, if possible, is able to customize your IV to be the most beneficial for you. Before receiving the IV, a medical professional should check your vitals and ensure that the formula is safe and compatible for you at that time.

At MTC, our sister brand and integrative regenerative and cellular medicine practice, we offer three blends to boost brain health and performance. One of which, TransformCognition, is designed specifically to improve cognitive function, learning, and memory. It boasts the following benefits:

• Increases mental sharpness and clarity
• Improves overall brain function
• Improves memory recall
• Quicker cognition
• Enhances certain aspects of learning

Education: Learn More about Aging Smart with Free Our Age Smart Guide!

Want to more about ways to maintain cognitive functioning as you age? Our Free Age Smart Guide, produced in conjunction with our sister integrative regenerative and cellular medicine clinic, provides lots of insight into the future of optimal aging! Get your free copy here: https://www.medicaltransformationcenter.com/age-smart-guide-download